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H Wedemeyer, XS He, M Nascimbeni, AR Davis, HB Greenberg, JH Hoofnagle, TJ Liang, H Alter, B Rehermann. (2002) " Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. " J Immunol 169. 3447-58 PMID: 12218168 | Abstract and Keywords

T Boettler, HC Spangenberg, C Neumann-Haefelin, E Panther, S Urbani, C Ferrari, HE Blum, F von Weizsäcker, R Thimme. (2005) " T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. " J Virol 79. 7860-7 PMID: 15919940 DOI: 10.1128/JVI.79.12.7860-7867.2005 | Abstract and Keywords

I Tester, S Smyk-Pearson, P Wang, A Wertheimer, E Yao, DM Lewinsohn, JE Tavis, HR Rosen. (2005) " Immune evasion versus recovery after acute hepatitis C virus infection from a shared source. " J Exp Med 201. 1725-31 PMID: 15939788 DOI: 10.1084/jem.20042284 | Abstract and Keywords

HC Spangenberg, S Viazov, N Kersting, C Neumann-Haefelin, D McKinney, M Roggendorf, F von Weizsäcker, HE Blum, R Thimme. (2005) " Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection. " Hepatology 42. 828-37 PMID: 16175596 DOI: 10.1002/hep.20856 | Abstract and Keywords

B Bengsch, HC Spangenberg, N Kersting, C Neumann-Haefelin, E Panther, F von Weizsäcker, HE Blum, H Pircher, R Thimme. (2007) " Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver. " J Virol 81. 945-53 PMID: 17079288 DOI: 10.1128/JVI.01354-06 | Abstract and Keywords

H Radziewicz, CC Ibegbu, ML Fernandez, KA Workowski, K Obideen, M Wehbi, HL Hanson, JP Steinberg, D Masopust, EJ Wherry, JD Altman, BT Rouse, GJ Freeman, R Ahmed, A Grakoui. (2007) " Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. " J Virol 81. 2545-53 PMID: 17182670 DOI: 10.1128/JVI.02021-06 | Abstract and Keywords

H Radziewicz, CC Ibegbu, H Hon, MK Osborn, K Obideen, M Wehbi, GJ Freeman, JL Lennox, KA Workowski, HL Hanson, A Grakoui. (2008) " Impaired hepatitis C virus (HCV)-specific effector CD8+ T cells undergo massive apoptosis in the peripheral blood during acute HCV infection and in the liver during the chronic phase of infection. " J Virol 82. 9808-22 PMID: 18667503 DOI: 10.1128/JVI.01075-08 | Abstract and Keywords

E Billerbeck, N Nakamoto, B Seigel, HE Blum, KM Chang, R Thimme. (2009) " Determinants of in vitro expansion of different human virus-specific FoxP3+ regulatory CD8+ T cells in chronic hepatitis C virus infection. " J Gen Virol 90. 1692-701 PMID: 19321758 DOI: 10.1099/vir.0.009837-0 | Abstract and Keywords

H Radziewicz, CC Ibegbu, H Hon, N Bédard, J Bruneau, KA Workowski, SJ Knechtle, AD Kirk, CP Larsen, NH Shoukry, A Grakoui. (2010) " Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. " J Immunol 184. 2410-22 PMID: 20100932 DOI: 10.4049/jimmunol.0902994 | Abstract and Keywords