Custom Class II Reagents - Check Premade List (Below) Before Using

(ex. DIYKGVYQFKSV)
(ex. LCMV)
(ex. glycoprotein)
(ex. 66-77)

Please check the pre-made list below before placing a custom request.

Peptide may need to be supplied for some reagents.

Please note, a human CLIP peptide-containing negative control reagent will be included with all orders.

Each unit of quantity contains 200 µg of MHC protein.

The Tetramer Resource Committee (TRC) meets approximately every other Friday to review tetramer requests. Requests must be received before 12 noon EST three days before a scheduled TRC meeting in order to be considered. View TRC Schedule

Click here for technical support.

Previously Made Class II

The class I MHC tetramers listed below are available as biotinylated monomers or as tetramers made with the listed fluorophore options. Requesters will receive approximately 200 micrograms of protein per unit of quantity.

Please note that the reagents listed on this page have been produced by the NIH Tetramer Facility with strict quality control (including gene sequencing, affinity purification, SDS PAGE analysis, and verification of biotinylation by immunoprecipitation), but many have not been confirmed to stain or activate specific T cells.

Some reagents may require you to send peptide to us in order to conduct a custom synthesis via peptide exchange. Once your order is approved, an email approval notification will be issued, including details regarding any peptide that needs to be supplied.

Allele Description Peptide Sequencesort descending Order Options Info
I-A(b) rotavirus VP6 245-259 ATWYFNPVILRPNNV
I-A(b) T. gondii TGME49__012300 605-619 AVEIHRPVPGTAPPS
DRB1*07:01 HCV NS2 732-753 AYCLWMMLLISQAEAALELIT
*
I-A(g7) chicken Ova 141-160 CARELINSWVESQTNGIIRN
I-A(d) LCMV GP 316-330 CDMLRLIDYNKAALS
I-A(b) mouse PLP 10-21 CLVGAPFASLVA
I-A(b) house dust mite Derp1 217-227 CQIYPPNVNKI
*
I-A(b) mouse TRP1 var C22A 113-126 CRPGWRGAAANQKI
*
I-A(b) mouse TRP1 113-126 CRPGWRGAACNQKI
*
I-A(d) LCMV GP 176-190 DAQSAQSQCRTFRGR
I-A(b) LCMV GP 66-77 DIYKGVYQFKSV
I-A(g7) rat CD23 216-231 DLKGRLVSIHSQKEQD
I-A(b) Bac flagellin 456-475 DMATEMVKYSNANILSQAGQ
*
I-A(k) DSAFDVLSFTAEEKAGVYK
I-A(g7) mouse ChgA 29-42 DTKVMKCVLEVISD

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Disclaimer: Please note that the reagents listed on this page have been produced by the NIH Tetramer Facility with strict quality control (including gene sequencing, affinity purification, SDS PAGE analysis, and verification of biotinylation by immunoprecipitation), but many have not been confirmed to stain or activate specific T cells.