The following publications acknowledge the NIH Tetramer Facility for providing reagents used in their research.

2006 Publications
Akbari, O., J. L. Faul, et al. (2006). "CD4+ Invariant T-Cell–Receptor+ Natural Killer T Cells in Bronchial Asthma." N Engl J Med 354(11): 1117-1129.

Comin-Anduix, B., A. Gualberto, et al. (2006). "Definition of an Immunologic Response Using the Major Histocompatibility Complex Tetramer and Enzyme-Linked Immunospot Assays." Clin Cancer Res 12(1): 107-116.

Dong, Y., J. Qian, et al. (2006). "Identification of H-2Db-specific CD8+ T-cell epitopes from mouse VEGRF2 that can inhibit angiogeneseis and tumor growth." Journal of Immunotherapy 29(1): 32-40.

Haas, A. R., J. Sun, et al. (2006). "Cycloxygenase-2 Inhibition Augments the Efficacy of a Cancer Vaccine." Clin Cancer Res 12(1): 214-222.

Ho, O. and W. R. Green (2006). "Cytolytic CD8+ T Cells Directed against a Cryptic Epitope Derived from a Retroviral Alternative Reading Frame Confer Disease Protection." J Immunol 176(4): 2470-2475.

Kassim, S. H., N. K. Rajasagi, et al. (2006). "In Vivo Ablation of CD11c-Positive Dendritic Cells Increases Susceptibility to Herpes Simplex Virus Type 1 Infection and Diminishes NK and T-Cell Responses." J Virol 80(8): 3985-3993.

Lopez-Albaitero, A., J. V. Nayak, et al. (2006). "Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTL." J Immunol 176(6): 3402-3409.

Manigold, T., E.-C. Shin, et al. (2006). "Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees recovered from Hepatitis C." Blood: 2005-09-3903.

Rich, R. F., W. J. Cook, et al. (2006). "Spontaneous in vivo retrovirus-infected T and B cells, but not dendritic cells, mediate antigen-specific Fas ligand/Fas-dependent apoptosis of anti-retroviral CTL." Virology 346(2): 287.

Sedgmen, B. J., W. Dawicki, et al. (2006). "LIGHT is dispensable for CD4+ and CD8+ T cell and antibody responses to influenza A virus in mice." Int Immunol: dxl016.

2005 Publications
Albers, A., K. Abe, et al. (2005). "Antitumor Activity of Human Papillomavirus Type 16 E7-Specific T Cells against Virally Infected Squamous Cell Carcinoma of the Head and Neck." Cancer Res 65(23): 11146-11155.

Albers, A., R. Ferris, et al. (2005). " Immune responses to p53 in patients with cancer:enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sites." Cancer Immunology, Immunotherapy 54(11): 1072.

Aoshi, T., M. Suzuki, et al. (2005). "Expression mapping using a retroviral vector for CD8+ T cell epitopes: Definition of a Mycobacterium tuberculosis peptide presented by H2-Dd." Journal of Immunological Methods 298(1-2): 21.

Badovinac, V., K. Messingham, et al. (2005). "Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination." Nature Medicine 11(7): 748-56.

Beadling, C. and M. K. Slifka (2005). "Differential regulation of virus-specific T-cell effector functions following activation by peptide or innate cytokines." Blood 105(3): 1179-1186.

Boettler, T., H. C. Spangenberg, et al. (2005). "T Cells with a CD4+CD25+ Regulatory Phenotype Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Chronic Hepatitis C Virus Infection." J Virol 79(12): 7860-7867.

Bukreyev, A., I. M. Belyakov, et al. (2005). "Expression of Interleukin-4 by Recombinant Respiratory Syncytial Virus Is Associated with Accelerated Inflammation and a Nonfunctional Cytotoxic T-Lymphocyte Response following Primary Infection but Not following Challenge with Wild-Type Virus." J Virol 79(15): 9515-9526.

Choi, C., M. Witzens, et al. (2005). "Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma." Blood 105(5): 2132-2134.

Crough, T., J. M. Burrows, et al. (2005). "Contemporaneous fluctuations in T cell responses to persistent herpes virus infections." European Journal of Immunology 35(1): 139-149.

Dikopoulos, N., A. Bertoletti, et al. (2005). "Type I IFN Negatively Regulates CD8+ T Cell Responses through IL-10-Producing CD4+ T Regulatory 1 Cells." J Immunol 174(1): 99-109.

Doan, T., K. Herd, et al. (2005). "A polytope DNA vaccine elicits multiple effector and memory CTL responses and protects against human papillomavirus 16 E7-expressing tumour." Cancer Immunology, Immunotherapy 54(2): 157.

Ercolini, A. M., B. H. Ladle, et al. (2005). "Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response." J Exp Med 201(10): 1591-1602.

Evans, D. T., J. E. Bricker, et al. (2005). "Immunization of Macaques with Single-Cycle Simian Immunodeficiency Virus (SIV) Stimulates Diverse Virus-Specific Immune Responses and Reduces Viral Loads after Challenge with SIVmac239." J Virol 79(12): 7707-7720.

Gray, P. M., S. Arimilli, et al. (2005). "Altered Function in CD8+ T Cells following Paramyxovirus Infection of the Respiratory Tract." J Virol 79(6): 3339-3349.

Gupta, M., P. Greer, et al. (2005). "CD8-Mediated Protection against Ebola Virus Infection Is Perforin Dependent." J Immunol 174(7): 4198-4202.

Harashima, N., R. Tanosaki, et al. (2005). "Identification of Two New HLA-A*1101-Restricted Tax Epitopes Recognized by Cytotoxic T Lymphocytes in an Adult T-Cell Leukemia Patient after Hematopoietic Stem Cell Transplantation." J Virol 79(15): 10088-10092.

Hobeika, A. C., M. A. Morse, et al. (2005). "Enumerating Antigen-Specific T-Cell Responses in Peripheral Blood: A Comparison of Peptide MHC Tetramer, ELISpot, and Intracellular Cytokine Analysis." Journal of Immunotherapy 28(1): 63-72.

Hodge, J. W., M. Chakraborty, et al. (2005). " Multiple Costimulatory Modalities Enhance CTL Avidity." J Immunol 174(10): 5994-6004.

Hossain, M. S., J. D. Roback, et al. (2005). "Amotosalen-treated donor T cells have polyclonal antigen-specific long-term function without graft-versus-host disease after allogeneic bone marrow transplantation." Biology of Blood and Marrow Transplantation 11(3): 169-180.

Hussain, S. F. and Y. Paterson (2005). "What is needed for effective antitumor immunotherapy? Lessons learned using Listeria monocytogenes as a live vector for HPV-associated tumors." Cancer Immunology, Immunotherapy 54(6): 577-586.

Jing, L., T. M. Chong, et al. (2005). "Diversity in the Acute CD8 T Cell Response to Vaccinia Virus in Humans." J Immunol 175(11): 7550-7559.

Kemball, C. C., E. D. H. Lee, et al. (2005). "Late Priming and Variability of Epitope-Specific CD8+ T Cell Responses during a Persistent Virus Infection." J Immunol 174(12): 7950-7960.

Koelle, D. M., J. C. Gonzalez, et al. (2005). "Homing in on the Cellular Immune Response to HSV-2 in Humans." Am J Reprod Immunol 53(4): 172-181.

Li, Z., X. Zhao, et al. (2005). "Conditional lethality yields a new vaccine strain of Listeria monocytogenes for the inducation of cell-mediated immunity." Infect Immun 73(8): 5065-5073.

Lieto, L. D., K. Maasho, et al. (2005). "The human CD94 gene encodes multiple, expressible transcripts including a new partner of NKG2A//B." Genes Immun 7(1): 36.

Maasho, K., J. Opoku-Anane, et al. (2005). "Cutting Edge: NKG2D Is a Costimulatory Receptor for Human Naive CD8+ T Cells." J Immunol 174(8): 4480-4484.

Macedo, C., A. Donnenberg, et al. (2005). "EBV-specific memory CD8+ T cell phenotype and function in stable solid organ transplant patients." Transplant Immunology 14(2): 109.

Martin, D. L. and R. L. Tarleton (2005). "Antigen-Specific T Cells Maintain an Effector Memory Phenotype during Persistent Trypanosoma cruzi Infection." J Immunol 174(3): 1594-1601.

Meraldi, V., J. F. Romero, et al. (2005). " A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites." Vaccine 23(21): 2801-2812.

Mrusek, S., S. Vallbracht, et al. (2005). "The impact of splenectomy on antiviral T cell memory in mice." Int Immunol 17(1): 27-33.

Niland, B., K. Banki, et al. (2005). "CD8+ T Cell-Mediated HLA-A*0201-Restricted Cytotoxicity to Transaldolase Peptide 168-176 in Patients with Multiple Sclerosis." J Immunol 175(12): 8365-8378.

Osada, T., M. A. Morse, et al. (2005). "Ex vivo expanded human CD4+ regulatory NKT cells suppress expansion of tumor antigen-specific CTLs." Int Immunol 17(9): 1143-1155.

Qureshi, M. H., B. A. Garvy, et al. (2005). "A murine model of dual infection with cytomegalovirus and Pneumocystis carinii: Effects of virus-induced immunomodulation on disease progression." Virus Research 114: 35-44.

Reynolds, M. R., E. Rakasz, et al. (2005). "CD8+ T-Lymphocyte Response to Major Immunodominant Epitopes after Vaginal Exposure to Simian Immunodeficiency Virus: Too Late and Too Little." J Virol 79(14): 9228-9235.

Rist, M., L. Cooper, et al. (2005). "Ex vivo expansion of human cytomegalovirus-specific cytotoxic T†cells by recombinant polyepitope: implications for HCMV immunotherapy." European Journal of Immunology 35(3): 996-1007.

Sabbaj, S., M. K. Ghosh, et al. (2005). "Breast Milk-Derived Antigen-Specific CD8+ T Cells: An Extralymphoid Effector Memory Cell Population in Humans." J Immunol 174(5): 2951-2956.

Straathof, K. C., A. M. Leen, et al. (2005). "Characterization of Latent Membrane Protein 2 Specificity in CTL Lines from Patients with EBV-Positive Nasopharyngeal Carcinoma and Lymphoma." J Immunol 175(6): 4137-4147.

Straathof, K. C. M., C. M. Bollard, et al. (2005). "Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes." Blood 105(5): 1898-1904.

Sugimoto, K., D. E. Kaplan, et al. (2005). "Strain-Specific T-Cell Suppression and Protective Immunity in Patients with Chronic Hepatitis C Virus Infection." J Virol 79(11): 6976-6983.

Tester, I., S. Smyk-Pearson, et al. (2005). "Immune evasion versus recovery after acute hepatitis C virus infection from a shared source." J Exp Med 201(11): 1725-1731.

Usherwood, E. J., S. K. Meadows, et al. (2005). "Control of murine gammaherpesvirus infection is independent of NK cells." European Journal of Immunology 35(10): 2956-2961.

van Rhee, F., S. M. Szmania, et al. (2005). "NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses." Blood 105(10): 3939-3944.

Vidric, M., W.-K. Suh, et al. (2005). "Cooperation between 4-1BB and ICOS in the Immune Response to Influenza Virus Revealed by Studies of CD28/ICOS-Deficient Mice." J Immunol 175(11): 7288-7296.

Wesley, J. D., S. H. Robbins, et al. (2005). "Cutting Edge: IFN-{gamma} Signaling to Macrophages Is Required for Optimal V{alpha}14i NK T/NK Cell Cross-Talk." J Immunol 174(7): 3864-3868.

Wille-Reece, U., C.-y. Wu, et al. (2005). "Immunization with HIV-1 Gag Protein Conjugated to a TLR7/8 Agonist Results in the Generation of HIV-1 Gag-Specific Th1 and CD8+ T Cell Responses." J Immunol 174(12): 7676-7683.

Zeng, R., R. Spolski, et al. (2005). "Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function." J Exp Med 201(1): 139-148.

Zhang, Y., G. Joe, et al. (2005). "Alloreactive Memory T Cells Are Responsible for the Persistence of Graft-versus-Host Disease." J Immunol 174(5): 3051-3058.

Zhao, X., Z. Li, et al. (2005). "Pathogenicity and immunogenicity of a vaccine strain of Listeria monocytogenes that relies on a suicide plasmid to supply an essential gene product." Infect Immun 73(9): 5789-5798.

Zimmerman, Z., A. Shatry, et al. (2005). "Effector Cells Derived from Host CD8 Memory T Cells Mediate Rapid Resistance against Minor Histocompatibility Antigen-Mismatched Allogeneic Marrow Grafts without Participation of Perforin, Fas Ligand, and the Simultaneous Inhibition of 3 Tumor Necrosis Factor Family Effector Pathways." Biology of Blood and Marrow Transplantation 11(8): 576-586.

2004 Publications
Berg-Brown, N. N., M. A. Gronski, et al. (2004). "PKC{theta} Signals Activation versus Tolerance In Vivo." J Exp Med 199(6): 743-752.

Bertley, F. M. N., P. A. Kozlowski, et al. (2004). "Control of Simian/Human Immunodeficiency Virus Viremia and Disease Progression after IL-2-Augmented DNA-Modified Vaccinia Virus Ankara Nasal Vaccination in Nonhuman Primates." J Immunol 172(6): 3745-3757.

Bertram, E. M., W. Dawicki, et al. (2004). "A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo." J Immunol 172(2): 981-988.

Blais, M.-E., G. Gerard, et al. (2004). "Do thymically and strictly extrathymically developing T cells generate similar immune responses?" Blood 103(8): 3102-3110.

Bollard, C. M., L. Aguilar, et al. (2004). "Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus+ Hodgkin's Disease." J Exp Med 200(12): 1623-1633.

Bollard, C. M., K. C. Straathof, et al. (2004). "The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease." Journal of Immunotherapy 27(4): 317-27.

Carlsson, B., T. H. Totterman, et al. (2004). "Generation of cytotoxic T lymphocytes specific for the prostate and breast tissue antigen TARP." The Prostate 61(2): 161-170.

Castiglioni, P., M. Gerloni, et al. (2004). "Genetically programmed B lymphocytes are highly efficient in inducing anti-virus protective immunity mediated by central memory CD8 T cells." Vaccine 23(5): 699-708.

Chen, W., K. Pang, et al. (2004). "Reversal in the Immunodominance Hierarchy in Secondary CD8+ T Cell Responses to Influenza A Virus: Roles for Cross-Presentation and Lysis-Independent Immunodomination." J Immunol 173(8): 5021-5027.

Chikhlikar, P., L. Barros de Arruda, et al. (2004). "Inverted terminal repeat sequences of adeno-associated virus enhance the antibody and CD8+ responses to a HIV-1 p55Gag/LAMP DNA vaccine chimera." Virology 323(2): 220-232.

Dagarag, M., T. Evazyan, et al. (2004). "Genetic Manipulation of Telomerase in HIV-Specific CD8+ T Cells: Enhanced Antiviral Functions Accompany the Increased Proliferative Potential and Telomere Length Stabilization." J Immunol 173(10): 6303-6311.

Dawicki, W., E. M. Bertram, et al. (2004). "4-1BB and OX40 Act Independently to Facilitate Robust CD8 and CD4 Recall Responses." J Immunol 173(10): 5944-5951.

De Arruda, L. B., P. R. Chikhlikar, et al. (2004). "DNA vaccine encoding human immunodeficiency virus-1 Gag, targeted to the major histocompatibility complex II compartment by lysosomal-associated membrane protein, elicits enhanced long-term memory response." Immunology 112(1): 126-135.

Deng, Y., Y. Jing, et al. (2004). "Age-Related Impaired Type 1 T Cell Responses to Influenza: Reduced Activation Ex Vivo, Decreased Expansion in CTL Culture In Vitro, and Blunted Response to Influenza Vaccination In Vivo in the Elderly." J Immunol 172(6): 3437-3446.

Dittmer, U., H. He, et al. (2004). "Functional Impairment of CD8+ T Cells by Regulatory T Cells during Persistent Retroviral Infection." Immunity 20(3): 293-303.

Ehl, S., R. Bischoff, et al. (2004). "The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus." European Journal of Immunology 34(4): 1146-1153.

Fassnacht, U., A. Ackermann, et al. (2004). "Immunization with dendritic cells can break immunological ignorance toward a persisting virus in the central nervous system and induce partial protection against intracerebral viral challenge." J Gen Virol 85(8): 2379-2387.

Fry, T. J., M. Sinha, et al. (2004). "Flt3 ligand enhances thymic-dependent and thymic-independent immune reconstitution." Blood 104(9): 2794-2800.

Gerloni, M., M. Rizzi, et al. (2004). "T cell immunity using transgenic B lymphocytes." PNAS 101(11): 3892-3897.

Hamilton, S., B. Porter, et al. (2004). "MHC class Ia-restricted memory T cells inhibit expansion of a nonprotective MHC

class Ib (H2-M3)-restricted memory response." Nature Immunology 5(2): 159-68.

Harashima, N., K. Kurihara, et al. (2004). "Graft-versus-Tax Response in Adult T-Cell Leukemia Patients after Hematopoietic Stem Cell Transplantation." Cancer Res 64(1): 391-399.

Ince, M. N., B. Harnisch, et al. (2004). " Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function." Immunology 112(4): 531-542.

Kamath, A. B., J. Woodworth, et al. (2004). "Cytolytic CD8+ T Cells Recognizing CFP10 Are Recruited to the Lung after Mycobacterium tuberculosis Infection." J Exp Med 200(11): 1479-1489.

Kan-Mitchell, J., B. Bisikirska, et al. (2004). "The HIV-1 HLA-A2-SLYNTVATL Is a Help-Independent CTL Epitope." J Immunol 172(9): 5249-5261.

Kristensen, N. N., A. N. Madsen, et al. (2004). "Cytokine production by virus-specific CD8+ T cells varies with activation state and localization, but not with TCR avidity." J Gen Virol 85(6): 1703-1712.

Kumaraguru, U., S. Suvas, et al. (2004). "Concomitant Helper Response Rescues Otherwise Low Avidity CD8+ Memory CTLs to Become Efficient Effectors In Vivo." J Immunol 172(6): 3719-3724.

Lange, C. G. a., Z. b. Xu, et al. (2004). "Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function." AIDS 18(4): 605-13.

Laucella, S. A., M. Postan, et al. (2004). "Frequency of interferon- gamma -producing T cells specific for Trypanosoma cruzi inversely correlates with disease severity in chronic human Chagas disease." J Infect Dis 189(5): 909-18.

Lieberman, S. M., T. Takaki, et al. (2004). "Individual Nonobese Diabetic Mice Exhibit Unique Patterns of CD8+ T Cell Reactivity to Three Islet Antigens, Including the Newly Identified Widely Expressed Dystrophia Myotonica Kinase." J Immunol 173(11): 6727-6734.

Lopez, C. B., B. Moltedo, et al. (2004). "TLR-Independent Induction of Dendritic Cell Maturation and Adaptive Immunity by Negative-Strand RNA Viruses." J Immunol 173(11): 6882-6889.

Lustgarten, J., A. L. Dominguez, et al. (2004). "Aged Mice Develop Protective Antitumor Immune Responses with Appropriate Costimulation." J Immunol 173(7): 4510-4515.

Melchionda, F., M. K. McKirdy, et al. (2004). "Escape from Immune Surveillance Does Not Result in Tolerance to Tumor-Associated Antigens." Journal of Immunotherapy 27(5): 329-38.

Messaoudi, I., J. LeMaoult, et al. (2004). "Age-related CD8 T Cell Clonal Expansions Constrict CD8 T Cell Repertoire and Have the Potential to Impair Immune Defense." J Exp Med 200(10): 1347-1358.

Moroz, A., C. Eppolito, et al. (2004). "IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21." J Immunol 173(2): 900-909.

Nussbaum, A. K. and J. L. Whitton (2004). "The Contraction Phase of Virus-Specific CD8+ T Cells Is Unaffected by a Pan-Caspase Inhibitor." J Immunol 173(11): 6611-6618.

Ogasawara, K., J. A. Hamerman, et al. (2004). "NKG2D Blockade Prevents Autoimmune Diabetes in NOD Mice." Immunity 20(6): 757-767.

Oh, S., L. P. Perera, et al. (2004). "IL-15/IL-15R{alpha}-mediated avidity maturation of memory CD8+ T cells." PNAS 101(42): 15154-15159.

Ortaldo, J. R., H. A. Young, et al. (2004). "Dissociation of NKT Stimulation, Cytokine Induction, and NK Activation In Vivo by the Use of Distinct TCR-Binding Ceramides." J Immunol 172(2): 943-953.

Publicover, J., E. Ramsburg, et al. (2004). "Characterization of Nonpathogenic, Live, Viral Vaccine Vectors Inducing Potent Cellular Immune Responses." J Virol 78(17): 9317-9324.

Quinto, I., A. Puca, et al. (2004). "High Attenuation and Immunogenicity of a Simian Immunodeficiency Virus Expressing a Proteolysis-resistant Inhibitor of NF-{kappa}B." J Biol Chem 279(3): 1720-1728.

Ramsburg, E., N. F. Rose, et al. (2004). "Highly Effective Control of an AIDS Virus Challenge in Macaques by Using Vesicular Stomatitis Virus and Modified Vaccinia Virus Ankara Vaccine Vectors in a Single-Boost Protocol." J Virol 78(8): 3930-3940.

Raue, H.-P., J. D. Brien, et al. (2004). "Activation of Virus-Specific CD8+ T Cells by Lipopolysaccharide-Induced IL-12 and IL-18." J Immunol 173(11): 6873-6881.

Ribas, A., J. A. Glaspy, et al. (2004). "Role of Dendritic Cell Phenotype, Determinant Spreading, and Negative Costimulatory Blockade in Dendritic Cell-Based Melanoma Immunotherapy." Journal of Immunotherapy 27(5): 354-367.

Seifert, U., H. Liermann, et al. (2004). "Hepatitis C virus mutation affects proteasomal epitope processing." J Clin Invest 114(2): 250-259.

Sewell, D. A., V. Shahabi, et al. (2004). "Recombinant Listeria Vaccines Containing PEST Sequences Are Potent Immune Adjuvants for the Tumor-Associated Antigen Human Papillomavirus-16 E7." Cancer Res 64(24): 8821-8825.

Sharpe, S. A., A. Cope, et al. (2004). "Macaques infected long-term with attenuated simian immunodeficiency virus (SIVmac) remain resistant to wild-type challenge, despite declining cytotoxic T lymphocyte responses to an immunodominant epitope." J Gen Virol 85(9): 2591-2602.

Takaki, T., S. M. Lieberman, et al. (2004). "Requirement for Both H-2Db and H-2Kd for the Induction of Diabetes by the Promiscuous CD8+ T Cell Clonotype AI4." J Immunol 173(4): 2530-2541.

Utting, O., B. J. Sedgmen, et al. (2004). "Immune Functions in Mice Lacking Clnk, an SLP-76-Related Adaptor Expressed in a Subset of Immune Cells." Mol Cell Biol 24(13): 6067-6075.

Verch, T., Z.-K. Pan, et al. (2004). "Listeria monocytogenes-Based Antibiotic Resistance Gene-Free Antigen Delivery System Applicable to Other Bacterial Vectors and DNA Vaccines." Infect Immun 72(11): 6418-6425.

Wang, S.-W., F. M. N. Bertley, et al. (2004). "An SHIV DNA/MVA Rectal Vaccination in Macaques Provides Systemic and Mucosal Virus-Specific Responses and Protection against AIDS." AIDS Research and Human Retroviruses 20(8): 846-859.

Wilcox, R. A., K. Tamada, et al. (2004). "Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo." Blood 103(1): 177-184.

Wu, Z., M. Roberts, et al. (2004). "Viral FLIP Impairs Survival of Activated T Cells and Generation of CD8+ T Cell Memory." J Immunol 172(10): 6313-6323.

Yamano, Y., C. J. Cohen, et al. (2004). "Increased Expression of Human T Lymphocyte Virus Type I (HTLV-I) Tax11-19 Peptide-Human Histocompatibility Leukocyte Antigen A*201 Complexes on CD4+ CD25+ T Cells Detected by Peptide-specific, Major Histocompatibility Complex-restricted Antibodies in Patients with HTLV-I-associated Neurologic Disease." J Exp Med 199(10): 1367-1377.

2003 Publications
Andreasen, S. O., A. R. Thomsen, et al. (2003). "Expression and Functional Importance of Collagen-Binding Integrins, {alpha}1{beta}1 and {alpha}2{beta}1, on Virus-Activated T Cells." J Immunol 171(6): 2804-2811.

Badovinac, V. P., S. E. Hamilton, et al. (2003). "Viral Infection Results in Massive CD8+ T Cell Expansion and Mortality in Vaccinated Perforin-Deficient Mice." Immunity 18(4): 463-474.

Bras-Goncalves, R., F.-A. Le Gal, et al. (2003). "In situ detection of antigen-specific tumor-infiltrating lymphocytes using newly designed tetramers." Journal of Immunological Methods 280(1-2): 103-111.

Bullock, T. N. J., D. W. Mullins, et al. (2003). "Antigen Density Presented By Dendritic Cells In Vivo Differentially Affects the Number and Avidity of Primary, Memory, and Recall CD8+ T Cells." J Immunol 170(4): 1822-1829.

Butterfield, L. H., A. Ribas, et al. (2003). "Determinant Spreading Associated with Clinical Response in Dendritic Cell-based Immunotherapy for Malignant Melanoma." Clin Cancer Res 9(3): 998-1008.

Butterfield, L. H., A. Ribas, et al. (2003). "T-Cell Responses to HLA-A*0201 Immunodominant Peptides Derived from {alpha}-Fetoprotein in Patients with Hepatocellular Cancer." Clin Cancer Res 9(16): 5902-5908.

Calzascia, T., W. Di Berardino-Besson, et al. (2003). "Cutting Edge: Cross-Presentation as a Mechanism for Efficient Recruitment of Tumor-Specific CTL to the Brain." J Immunol 171(5): 2187-2191.

Cavanaugh, V. J., Y. Deng, et al. (2003). "Vigorous Innate and Virus-Specific Cytotoxic T-Lymphocyte Responses to Murine Cytomegalovirus in the Submaxillary Salivary Gland." J Virol 77(3): 1703-1717.

Cheng, W. F., C. F. Hung, et al. (2003). "Cd8+ T cells, NK cells and INF-gamma are important for contraol of tumor with downregulated MHC class I expression by DNA vaccination." Gene Therapy 10: 1311-1320.

Christensen, J. P., S. O. Kauffmann, et al. (2003). "Deficient CD4+ T Cell Priming and Regression of CD8+ T Cell Functionality in Virus-Infected Mice Lacking a Normal B Cell Compartment." J Immunol 171(9): 4733-4741.

Da Silva, D. M., J. T. Schiller, et al. (2003). "Heterologous boosting increases immunogenicity of chimeric papillomavirus virus-like particle vaccines." Vaccine 21(23): 3219-3227.

Dagarag, M., H. Ng, et al. (2003). "Differential Impairment of Lytic and Cytokine Functions in Senescent Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes." J Virol 77(5): 3077-3083.

Dionne, S. O., M. H. Smith, et al. (2003). "Functional characterization of CTL against gp100 altered peptide ligands." Cancer Immunology, Immunotherapy 52(4): 199-206.

Ewen, C., K. P. Kane, et al. (2003). " A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for Granzyme B." Journal of Immunological Methods 276(1-2): 89-101.

Fitzgerald, J. C., G.-P. Gao, et al. (2003). "A Simian Replication-Defective Adenoviral Recombinant Vaccine to HIV-1 Gag." J Immunol 170(3): 1416-1422.

Gandhi, M. K., M. R. Wills, et al. (2003). "Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation." Blood 102(9): 3427-3438.

Glazyrin, A. L., J. Kan-Mitchell, et al. (2003). "Analysis of in vitro immunization: generation of cytotoxic T-lymphocytes against allogeneic melanoma cells with tumor lysate-loaded or tumor RNA-transfected antigen-presenting cells." Cancer Immunology, Immunotherapy 52(3): 171-178.

Gunturi, A., R. E. Berg, et al. (2003). "Preferential Survival of CD8 T and NK Cells Expressing High Levels of CD94." J Immunol 170(4): 1737-1745.

Hafalla, J. C. R., A. Morrot, et al. (2003). "Early Self-Regulatory Mechanisms Control the Magnitude of CD8+ T Cell Responses Against Liver Stages of Murine Malaria." J Immunol 171(2): 964-970.

Haridas, V., T. W. McCloskey, et al. (2003). "Discordant expression of perforin and granzyme A in total and HIV-specific CD8 T lymphocytes of HIV infected children and adolescents." AIDS 17(16): 2313-22.

Holler, P. D. and D. M. Kranz (2003). "Quantitative Analysis of the Contribution of TCR/pepMHC Affinity and CD8 to T Cell Activation." Immunity 18(2): 255-264.

Humphreys, I. R., G. Walzl, et al. (2003). "A Critical Role for OX40 in T Cell-mediated Immunopathology during Lung Viral Infection." J Exp Med 198(8): 1237-1242.

Khanna, K. M., R. H. Bonneau, et al. (2003). "Herpes Simplex Virus-Specific Memory CD8+ T Cells Are Selectively Activated and Retained in Latently Infected Sensory Ganglia." Immunity 18(5): 593-603.

Kotecha, M. T., R. K. Afghan, et al. (2003). "Enhanced tumour growth after DNA vaccination against human papilloma virus E7 oncoprotein: evidence for tumour-induced immune deviation." Vaccine 21(19-20): 2506-2515.

Lee, P. U. Y. and D. M. Kranz (2003). "Allogeneic and syngeneic class I MHC complexes drive the association of CD8 and TCR on 2C T cells." Molecular Immunology 39(12): 687-695.

Lewicki, H., A. Tishon, et al. (2003). "T Cells Infiltrate the Brain in Murine and Human Transmissible Spongiform Encephalopathies." J Virol 77(6): 3799-3808.

Ling, C., M. Sandor, et al. (2003). "In situ processing and distribution of intracerebrally injected OVA in the CNS." Journal of Neuroimmunology 141(1-2): 90-98.

Lopes, A. R., A. Jaye, et al. (2003). "Greater CD8+ TCR Heterogeneity and Functional Flexibility in HIV-2 Compared to HIV-1 Infection." J Immunol 171(1): 307-316.

Luznik, L., J. E. Slansky, et al. (2003). "Successful therapy of metastatic cancer using tumor vaccines in mixed allogeneic bone marrow chimeras." Blood 101(4): 1645-1652.

Lybarger, L., Y. Y. L. Yu, et al. (2003). "Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide." J Biol Chem 278(29): 27105-27111.

Mahnke, Y. D. and V. Schirrmacher (2003). "A novel tumour model system for the study of long-term protective immunity and immune T cell memory." Cellular Immunology 221(2): 89-99.

Malkevitch, N., L. J. Patterson, et al. (2003). "A Replication Competent Adenovirus 5 Host Range Mutant-Simian Immunodeficiency Virus (SIV) Recombinant Priming/Subunit Protein Boosting Vaccine Regimen Induces Broad, Persistent SIV-Specific Cellular Immunity to Dominant and Subdominant Epitopes in Mamu-A*01 Rhesus Macaques." J Immunol 170(8): 4281-4289.

Marques, E. T. A., Jr., P. Chikhlikar, et al. (2003). "HIV-1 p55Gag Encoded in the Lysosome-associated Membrane Protein-1 as a DNA Plasmid Vaccine Chimera Is Highly Expressed, Traffics to the Major Histocompatibility Class II Compartment, and Elicits Enhanced Immune Responses." J Biol Chem 278(39): 37926-37936.

Mason, L. H., J. Willette-Brown, et al. (2003). "Receptor Glycosylation Regulates Ly-49 Binding to MHC Class I." J Immunol 171(8): 4235-4242.

McPherson, S. W., J. Yang, et al. (2003). "Resting CD8 T cells recognize beta-galactosidase expressed in the immune-privileged retina and mediate autoimmune disease when activated." Immunology 110(3): 386-396.

Messingham, K. A. N., V. P. Badovinac, et al. (2003). "Deficient Anti-Listerial Immunity in the Absence of Perforin Can Be Restored by Increasing Memory CD8+ T Cell Numbers." J Immunol 171(8): 4254-4262.

Mullins, D. W., S. L. Sheasley, et al. (2003). "Route of Immunization with Peptide-pulsed Dendritic Cells Controls the Distribution of Memory and Effector T Cells in Lymphoid Tissues and Determines the Pattern of Regional Tumor Control." J Exp Med 198(7): 1023-1034.

Nascimbeni, M., E. Mizukoshi, et al. (2003). "Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees." J Virol 77(8): 4781-4793.

Oh, S., J. A. Berzofsky, et al. (2003). "Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity." PNAS 100(6): 3392-3397.

Oh, S., J. W. Hodge, et al. (2003). "Selective Induction of High Avidity CTL by Altering the Balance of Signals from APC." J Immunol 170(5): 2523-2530.

Ostler, T., H. Pircher, et al. (2003). " "Bystander" recruitment of systemic memory T†cells delays the immune response to respiratory virus infection." European Journal of Immunology 33(7): 1839-1848.

Peters, C., X. Peng, et al. (2003). "The Induction of HIV Gag-Specific CD8+ T Cells in the Spleen and Gut-Associated Lymphoid Tissue by Parenteral or Mucosal Immunization with Recombinant Listeria monocytogenes HIV Gag." J Immunol 170(10): 5176-5187.

Pietra, G., C. Romagnani, et al. (2003). "HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes." PNAS 100(19): 10896-10901.

Popescu, I., C. Macedo, et al. (2003). "Ex vivo priming of naive T cells into EBV-specific Th1/Tc1 effector cells by mature autologous DC loaded with apoptotic/necrotic LCL." Am J Transplantation 3(11): 1369-1377.

Rao, R. D. M. D., P. M. M. D. P. Anderson, et al. (2003). "Aerosolized Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) Therapy in Metastatic Cancer." Am J Clin Onc 26(5): 493-98.

Rayevskaya, M., N. Kushnir, et al. (2003). "Anti-human immunodeficiency virus-gag CD8+ memory T cells generated in vitro from Listeria-immunized mice." Immunology 109(3): 450-460.

Roback, J. D., M. S. Hossain, et al. (2003). "Allogeneic T Cells Treated with Amotosalen Prevent Lethal Cytomegalovirus Disease without Producing Graft-versus-Host Disease Following Bone Marrow Transplantation." J Immunol 171(11): 6023-6031.

Rubinstein, M. P., A. N. Kadima, et al. (2003). "Transfer of TCR Genes into Mature T Cells Is Accompanied by the Maintenance of Parental T Cell Avidity." J Immunol 170(3): 1209-1217.

Shoukry, N. H., A. Grakoui, et al. (2003). "Memory CD8+ T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection." J Exp Med 197(12): 1645-1655.

Sica, G. L., I.-H. Choi, et al. (2003). "B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity." Immunity 18(6): 849-861.

Sili, U., M. H. Huls, et al. (2003). "Large-Scale Expansion of Dendritic Cell-Primed Polyclonal Human Cytotoxic T-Lymphocyte Lines Using Lymphoblastoid Cell Lines for Adoptive Immunotherapy." Journal of Immunotherapy 26(3): 241-56.

Slifka, M. K., J. N. Blattman, et al. (2003). "Preferential Escape of Subdominant CD8+ T Cells During Negative Selection Results in an Altered Antiviral T Cell Hierarchy." J Immunol 170(3): 1231-1239.

Spiotto, M. T., M. A. Reth, et al. (2003). "Genetic changes occurring in established tumors rapidly stimulate new antibody responses." PNAS 100(9): 5425-5430.

Strbo, N., S. Oizumi, et al. (2003). "Perforin Is Required for Innate and Adaptive Immunity Induced by Heat Shock Protein Gp96." Immunity 18(3): 381-390.

Suh, W.-K., B. U. Gajewska, et al. (2003). "The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses." Nature Immunology 4(9): 899.

Tanaka, Y., S. F. Dowdy, et al. (2003). "Induction of Antigen-Specific CTL by Recombinant HIV Trans-Activating Fusion Protein-Pulsed Human Monocyte-Derived Dendritic Cells." J Immunol 170(3): 1291-1298.

Tomaru, U., Y. Yamano, et al. (2003). " Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections." Nature Medicine 9(4): 469.

Toomey, J. A., F. Gays, et al. (2003). "Cytokine requirements for the growth and development of mouse NK cells in vitro." J Leukoc Biol 74(2): 233-242.

Uhlin, M., M. G. Masucci, et al. (2003). "Pharmacological Disintegration of Lipid Rafts Decreases Specific Tetramer Binding and Disrupts the CD3 Complex and CD8 Heterodimer in Human Cytotoxic T Lymphocytes." Scandinavian Journal of Immunology 57(2): 99-106.

Villacres, M. C., S. F. Lacey, et al. (2003). "Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity." J Infect Dis 188(6): 908-18.

Wang, X., M. Messerle, et al. (2003). "Murine Cytomegalovirus Abortively Infects Human Dendritic Cells, Leading to Expression and Presentation of Virally Vectored Genes." J Virol 77(13): 7182-7192.

Wang, X., R. D. Wiley, et al. (2003). "Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming." Vaccine 21(19-20): 2288-2297.

Wheeler, C. J., K. L. Black, et al. (2003). "Thymic CD8+ T Cell Production Strongly Influences Tumor Antigen Recognition and Age-Dependent Glioma Mortality." J Immunol 171(9): 4927-4933.

Zhang, D., P. Shankar, et al. (2003). "Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic." Blood 101(1): 226-235.

Zhao, J., Y. Lou, et al. (2003). "Boosting of SIV-specific immune responses in rhesus macaques by repeated administration of Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinants." Vaccine 21(25-26): 4022-4035.

2002 Publications
Ansari, A. A., A. E. Mayne, et al. (2002). "Administration of Recombinant Rhesus Interleukin-12 during Acute Simian Immunodeficiency Virus (SIV) Infection Leads to Decreased Viral Loads Associated with Prolonged Survival in SIVmac251-Infected Rhesus Macaques." J Virol 76(4): 1731-1743.

Badovinac, V. P., B. B. Porter, et al. (2002). "Programmed contraction of CD8+ T cells after infection." Nature Immunology 3(7): 619.

Banerjee, K., S. Deshpande, et al. (2002). "Herpetic stromal keratitis in the absence of viral antigen recognition." Cellular Immunology 219(2): 108-118.

Bertram, E. M., P. Lau, et al. (2002). "Temporal Segregation of 4-1BB Versus CD28-Mediated Costimulation: 4-1BB Ligand Influences T Cell Numbers Late in the Primary Response and Regulates the Size of the T Cell Memory Response Following Influenza Infection." J Immunol 168(8): 3777-3785.

Bertram, E. M., A. Tafuri, et al. (2002). "Role of ICOS versus CD28 in antiviral immunity." European Journal of Immunology 32(12): 3376-3385.

Christensen, J. E., J. P. Christensen, et al. (2002). "Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells." Int Immunol 14(7): 701-711.

Fraser, K. P., F. Gays, et al. (2002). "NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time-dependent and stochastic manner independently of CD94 and NKG2." European Journal of Immunology 32(3): 868-878.

Ge, Q., J. D. Stone, et al. (2002). "Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules." PNAS 99(21): 13729-13734.

Gierynska, M., U. Kumaraguru, et al. (2002). "Induction of CD8 T-Cell-Specific Systemic and Mucosal Immunity against Herpes Simplex Virus with CpG-Peptide Complexes." J Virol 76(13): 6568-6576.

Hafalla, J. C. R., G.-i. Sano, et al. (2002). "Short-term antigen presentation and single clonal burst limit the magnitude of the CD8+ T cell responses to malaria liver stages." PNAS 99(18): 11819-11824.

Haglund, K., I. Leiner, et al. (2002). "High-Level Primary CD8+ T-Cell Response to Human Immunodeficiency Virus Type 1 Gag and Env Generated by Vaccination with Recombinant Vesicular Stomatitis Viruses." J Virol 76(6): 2730-2738.

Haglund, K., I. Leiner, et al. (2002). "Robust Recall and Long-Term Memory T-Cell Responses Induced by Prime-Boost Regimens with Heterologous Live Viral Vectors Expressing Human Immunodeficiency Virus Type 1 Gag and Env Proteins." J Virol 76(15): 7506-7517.

Hernandez, J., F. Garcia-Pons, et al. (2002). "Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells." PNAS 99(19): 12275-12280.

Hocknell, P. K., R. D. Wiley, et al. (2002). "Expression of Human Immunodeficiency Virus Type 1 gp120 from Herpes Simplex Virus Type 1-Derived Amplicons Results in Potent, Specific, and Durable Cellular and Humoral Immune Responses." J Virol 76(11): 5565-5580.Hoffmann, T. K., D. J. Loftus, et al. (2002). "The Ability of Variant Peptides to Reverse the Nonresponsiveness of T Lymphocytes to the Wild-Type Sequence p53264-272 Epitope." J Immunol 168(3): 1338-1347.

Kawana-Tachikawa, A., M. Tomizawa, et al. (2002). "An Efficient and Versatile Mammalian Viral Vector System for Major Histocompatibility Complex Class I/Peptide Complexes." J Virol 76(23): 11982-11988.

Koelle, D. M., Z. Liu, et al. (2002). "Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus." J Clin Invest 110(4): 537-548.

Kristensen, N. N., J. P. Christensen, et al. (2002). "High numbers of IL-2-producing CD8+ T cells during viral infection: correlation with stable memory development." J Gen Virol 83(9): 2123-2133.

La Rosa, C., Z. Wang, et al. (2002). "Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice." Blood 100(10): 3681-3689.

Laderach, D., M. Movassagh, et al. (2002). "4-1BB co-stimulation enhances human CD8+ T cell priming by augmenting the proliferation and survival of effector CD8+ T cells." Int Immunol 14(10): 1155-1167.

McCloskey, T. W., V. Haridas, et al. (2002). "T cell receptor V[beta] repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children." AIDS 16(11): 1459-65.

Mothe, B. R., H. Horton, et al. (2002). "Dominance of CD8 Responses Specific for Epitopes Bound by a Single Major Histocompatibility Complex Class I Molecule during the Acute Phase of Viral Infection." J Virol 76(2): 875-884.

Newton, D. A., P. M. Acierno, et al. (2002). "Semi-Allogeneic Vaccines for Patients With Cancer and AIDS." Journal of Immunotherapy 25(4): 334-41.

Nguyen, L. T., A. R. Elford, et al. (2002). "Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance." J Exp Med 195(4): 423-435.

Ostler, T., W. Davidson, et al. (2002). "Virus clearance and immunopathology by CD8+ T cells during infection with respiratory syncytial virus are mediated by IFN-gamma." European Journal of Immunology 32(8): 2117-2123.

Ostler, T. and S. Ehl (2002). "Pulmonary T cells induced by respiratory syncytial virus are functional and can make an important contribution to long-lived protective immunity." European Journal of Immunology 32(9): 2562-2569.

Pewe, L. and S. Perlman (2002). "Cutting Edge: CD8 T Cell-Mediated Demyelination Is IFN-{gamma} Dependent in Mice Infected with a Neurotropic Coronavirus." J Immunol 168(4): 1547-1551.

Pien, G. C., K. B. Nguyen, et al. (2002). "A Unique Mechanism for Innate Cytokine Promotion of T Cell Responses to Viral Infections." J Immunol 169(10): 5827-5837.

Poluektova, L. Y., D. H. Munn, et al. (2002). "Generation of Cytotoxic T Cells Against Virus-Infected Human Brain Macrophages in a Murine Model of HIV-1 Encephalitis." J Immunol 168(8): 3941-3949.

Porcu, P., C. F. Eisenbeis, et al. (2002). "Successful treatment of posttransplantation lymphoproliferative disorder (PTLD) following renal allografting is associated with sustained CD8+ T-cell restoration." Blood 100(7): 2341-2348.

Rich, R. F. and W. R. Green (2002). "Characterization of the Fas Ligand/Fas-Dependent Apoptosis of Antiretroviral, Class I MHC Tetramer-Defined, CD8+ CTL by In Vivo Retrovirus-Infected Cells." J Immunol 168(6): 2751-2758.

Rossig, C., C. M. Bollard, et al. (2002). "Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy." Blood 99(6): 2009-2016.

Sabbaj, S., B. H. Edwards, et al. (2002). "Human Immunodeficiency Virus-Specific CD8+ T Cells in Human Breast Milk." J Virol 76(15): 7365-7373.

Schulz, O., D. J. Pennington, et al. (2002). "CD36 or {alpha}v{beta}3 and {alpha}v{beta}5 Integrins Are Not Essential for MHC Class I Cross-Presentation of Cell-Associated Antigen by CD8{alpha}+ Murine Dendritic Cells." J Immunol 168(12): 6057-6065.

Singh, R. A. K., J. R. Rodgers, et al. (2002). "The Role of T Cell Antagonism and Original Antigenic Sin in Genetic Immunization." J Immunol 169(12): 6779-6786.

Singh, R. A. K., L. Wu, et al. (2002). "Generation of Genome-Wide CD8 T Cell Responses in HLA-A*0201 Transgenic Mice by an HIV-1 Ubiquitin Expression Library Immunization Vaccine." J Immunol 168(1): 379-391.

Street, M. D., T. Doan, et al. (2002). "Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus type 16 E7 protein." Immunology 106(4): 526-536.

Velupillai, P., J. P. Carroll, et al. (2002). "Susceptibility to Polyomavirus-Induced Tumors in Inbred Mice: Role of Innate Immune Responses." J Virol 76(19): 9657-9663.

Wedemeyer, H., X.-S. He, et al. (2002). " Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection." J Immunol 169(6): 3447-3458.

Wei, C.-H., M. Uhlin, et al. (2002). "Tetramer binding and secretion of interferon-[gamma] in response to antigenic stimulation are compatible with a range of affinities of MHC:TCR interaction and distinct programs of cytotoxic T-lymphocyte activation." Human Immunology 63(10): 821-833.

Wherry, E. J., M. J. McElhaugh, et al. (2002). "Generation of CD8+ T Cell Memory in Response to Low, High, and Excessive Levels of Epitope." J Immunol 168(9): 4455-4461.

Wills, M. R., G. Okecha, et al. (2002). "Identification of Naive or Antigen-Experienced Human CD8+ T Cells by Expression of Costimulation and Chemokine Receptors: Analysis of the Human Cytomegalovirus-Specific CD8+ T Cell Response." J Immunol 168(11): 5455-5464.

Yamano, Y., M. Nagai, et al. (2002). "Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8+ T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP)." Blood 99(1): 88-94.

Zhu, F. and D. D. Eckels (2002). " Functionally distinct helper T-cell epitopes of HCV and their role in modulation of NS3-specific, CD8+/tetramer positive CTL." Human Immunology 63(9): 710-718.

2001 Publications
Azimi, N., M. Nagai, et al. (2001). "IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients." PNAS 98(25): 14559-14564.

Bathe, O. F., N. Dalyot-Herman, et al. (2001). "IL-2 During In Vitro Priming Promotes Subsequent Engraftment and Successful Adoptive Tumor Immunotherapy by Persistent Memory Phenotypic CD8+ T Cells." J Immunol 167(8): 4511-4517.

Bullock, T. N. J., D. W. Mullins, et al. (2001). "Manipulation of Avidity to Improve Effectiveness of Adoptively Transferred CD8+ T Cells for Melanoma Immunotherapy in Human MHC Class I-Transgenic Mice." J Immunol 167(10): 5824-5831.

Chen, G., P. Shankar, et al. (2001). "CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection." Blood 98(1): 156-164.

Chen, W., C. C. Norbury, et al. (2001). "Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral CD8+ T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens." J Exp Med 193(11): 1319-1326.

Cho, B. K., K.-C. Lian, et al. (2001). "Differences in antigen recognition and cytolytic activity of CD8+ and CD8- T cells that express the same antigen-specific receptor." PNAS 98(4): 1723-1727.

Christen, U., T. Wolfe, et al. (2001). "A Dual Role for TNF-{{alpha}} in Type 1 Diabetes: Islet-Specific Expression Abrogates the Ongoing Autoimmune Process When Induced Late but Not Early During Pathogenesis." J Immunol 166(12): 7023-7032.

Christensen, J. E., S. O. Andreasen, et al. (2001). "CD11b expression as a marker to distinguish between recently activated effector CD8+ T cells and memory cells." Int Immunol 13(4): 593-600.

Christensen, J. P., C. Bartholdy, et al. (2001). "Depletion of CD4+ T Cells Precipitates Immunopathology in Immunodeficient Mice Infected with a Noncytocidal Virus." J Immunol 166(5): 3384-3391.

Edelmann, K. H. and C. B. Wilson (2001). "Role of CD28/CD80-86 and CD40/CD154 Costimulatory Interactions in Host Defense to Primary Herpes Simplex Virus Infection." J Virol 75(2): 612-621.

Fujii, S.-i., K. Shimizu, et al. (2001). "Interleukin-10 promotes the maintenance of antitumor CD8+ T-cell effector function in situ." Blood 98(7): 2143-2151.

Gahn, B., F. Siller-Lopez, et al. (2001). "Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: A potential treatment strategy for Epstein-Barr virus-positive Hodgkin's lymphoma." International Journal of Cancer 93(5): 706-713.

Gunn, G. R., A. Zubair, et al. (2001). "Two Listeria monocytogenes Vaccine Vectors That Express Different Molecular Forms of Human Papilloma Virus-16 (HPV-16) E7 Induce Qualitatively Different T Cell Immunity That Correlates with Their Ability to Induce Regression of Established Tumors Immortalized by HPV-16." J Immunol 167(11): 6471-6479.

Hernandez, J., A. Ko, et al. (2001). "CTLA-4 Blockade Enhances the CTL Responses to the p53 Self-Tumor Antigen." J Immunol 166(6): 3908-3914.

Koelle, D. M., H. B. Chen, et al. (2001). "CD8 CTL from Genital Herpes Simplex Lesions: Recognition of Viral Tegument and Immediate Early Proteins and Lysis of Infected Cutaneous Cells." J Immunol 166(6): 4049-4058.

Kowalczyk, D. W., A. P. Wlazlo, et al. (2001). "A method that allows easy characterization of tumor-infiltrating lymphocytes." Journal of Immunological Methods 253(1-2): 163-175.

Makrigiannis, A. P., A. T. Pau, et al. (2001). "Class I MHC-Binding Characteristics of the 129/J Ly49 Repertoire." J Immunol 166(8): 5034-5043.

McGettigan, J. P., S. Sarma, et al. (2001). "Expression and Immunogenicity of Human Immunodeficiency Virus Type 1 Gag Expressed by a Replication-Competent Rhabdovirus-Based Vaccine Vector." J Virol 75(18): 8724-8732.

Migueles, S. A. and M. Connors (2001). "Frequency and function of HIV-specific CD8+ T Cells." Immunology Letters 79(1-2): 141-150.

Mohamadzadeh, M., F. Berard, et al. (2001). "Interleukin 15 Skews Monocyte Differentiation into Dendritic Cells with Features of Langerhans Cells." J Exp Med 194(7): 1013-1020.

Nagai, M., Y. Yamano, et al. (2001). "Increased HTLV-I proviral load and preferential expansion of HTLV-I tax-specific CD8+ T cells in cerebrospinal fluid from patients with HAM/TSP." Annals of Neurology 50(6): 807-812.

Piccirillo, C. A. and E. M. Shevach (2001). "Cutting Edge: Control of CD8+ T Cell Activation by CD4+CD25+ Immunoregulatory Cells." J Immunol 167(3): 1137-1140.

Sakai, J. A., M. Nagai, et al. (2001). "In vitro spontaneous lymphoproliferation in patients with human T-cell lymphotropic virus type I-associated neurologic disease: predominant expansion of CD8+ T cells." Blood 98(5): 1506-1511.

Sano, G.-i., J. C. R. Hafalla, et al. (2001). "Swift Development of Protective Effector Functions in Naive CD8+ T Cells Against Malaria Liver Stages." J Exp Med 194(2): 173-180.

Slifka, M. K. and L. Whitton (2001). "Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR." Nature Immunology 2: 711-717.

Szmania, S., A. Galloway, et al. (2001). "Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers." Blood 98(3): 505-512.

Thimme, R., D. Oldach, et al. (2001). "Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection." J Exp Med 194(10): 1395-1406.

Tindle, R. W., K. Herd, et al. (2001). "Nonspecific Down-Regulation of CD8+ T-Cell Responses in Mice Expressing Human Papillomavirus Type 16 E7 Oncoprotein from the Keratin-14 Promoter." J Virol 75(13): 5985-5997.

Velders, M. P., S. Weijzen, et al. (2001). "Defined Flanking Spacers and Enhanced Proteolysis Is Essential for Eradication of Established Tumors by an Epitope String DNA Vaccine." J Immunol 166(9): 5366-5373.

Weijzen, S., S. C. Meredith, et al. (2001). "Pharmacokinetic Differences Between a T Cell-Tolerizing and a T Cell-Activating Peptide." J Immunol 166(12): 7151-7157.

Zhang, X. L., S. Zhao, et al. (2001). "CD8 Expression Up to the Double-Positive CD3Low/Intermediate Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes." J Exp Med 194(5): 685-694.

2000 Publications
Badovinac, V. P., G. A. Corbin, et al. (2000). " Cutting Edge: OFF Cycling of TNF Production by Antigen-Specific CD8+ T Cells Is Antigen Independent." J Immunol 165(10): 5387-5391.

Badovinac, V. P., A. R. Tvinnereim, et al. (2000). "Regulation of Antigen-Specific CD8+ T Cell Homeostasis by Perforin and Interferon-gamma." Science 290(5495): 1354-1357.Hoffmann, T. K., V. S. Donnenberg, et al. (2000). " Competition of peptide-MHC class I tetrameric complexes with anti-CD3 provides evidence for specificity of peptide binding to the TCR complex." Cytometry 41(4): 321-328.

Hoffmann, T. K., K. Nakano, et al. (2000). "Generation of T Cells Specific for the Wild-Type Sequence p53264-272 Peptide in Cancer Patients: Implications for Immunoselection of Epitope Loss Variants." J Immunol 165(10): 5938-5944.

Kowalczyk, D. W., A. P. Wlazlo, et al. (2000). "Staining of antigen activated lymphocytes (SAAL): a highly specific method for flow cytometric quantitation of tumor-specific CD8+ T cells." Journal of Immunological Methods 241(1-2): 131-139.

Migueles, S. A., M. S. Sabbaghian, et al. (2000). "HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors." PNAS 97(6): 2709-2714.

Rinaldo, C. R., Jr., X.-L. Huang, et al. (2000). "Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8+ T-Lymphocyte Reactivity during Combination Antiretroviral Therapy in HIV-1-Infected Patients with Advanced Immunodeficiency." J Virol 74(9): 4127-4138.